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Functional Annotation with EggNOG

Introduction

The Metagenomics module provides high-throughput functional annotation under Annotation Tools. The main options are orthology-based annotation with eggNOG and domain annotation with Pfam.

EggNOG Mapper

Use Functional Annotation with EggNOG Mapper for GO terms, COG categories, KEGG orthology, and eggNOG orthologous groups. Wizard parameters, results, and references are documented on the dedicated page:

Functional Annotation with EggNOG Mapper

Menu path: Metagenomics → Annotation Tools → Functional Annotation with EggNOG Mapper.

The same tool is also available under Functional Analysis → Functional Annotation with EggNOG Mapper.

PfamScan

Use PfamScan to assign Pfam protein domains and families. See:

Functional Annotation with PfamScan

Menu path: Metagenomics → Annotation Tools → PfamScan.